Jürgen Wess Selected Research

Muscarinic M3 Receptor

1/2015	Muscarinic M3 receptors on structural cells regulate cigarette smoke-induced neutrophilic airway inflammation in mice.
1/2015	The M3 muscarinic receptor is required for optimal adaptive immunity to helminth and bacterial infection.
4/2014	Muscarinic M₃ receptors contribute to allergen-induced airway remodeling in mice.
5/2008	Genetic ablation of M3 muscarinic receptors attenuates murine colon epithelial cell proliferation and neoplasia.

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Jürgen Wess Research Topics

Disease

16	Type 2 Diabetes Mellitus (MODY) 10/2021 - 06/2006
14	Insulin Resistance 10/2022 - 11/2006
9	Obesity 01/2022 - 11/2006
8	Glucose Intolerance 01/2022 - 06/2006
8	Inflammation (Inflammations) 12/2020 - 01/2009
5	Hyperglycemia 10/2021 - 12/2009
5	Schizophrenia (Dementia Praecox) 09/2016 - 02/2010
5	Chronic Obstructive Pulmonary Disease (COPD) 01/2015 - 12/2003
4	Alzheimer Disease (Alzheimer's Disease) 12/2018 - 11/2004
4	Parkinson Disease (Parkinson's Disease) 11/2015 - 04/2011
4	Asthma (Bronchial Asthma) 01/2013 - 12/2003
3	Body Weight (Weight, Body) 01/2021 - 01/2013
3	Nephrogenic Diabetes Insipidus 07/2014 - 05/2004
3	Insulinoma 10/2012 - 04/2010
2	Substance-Related Disorders (Drug Abuse) 01/2018 - 01/2012
2	Dyskinesias (Dyskinesia) 01/2016 - 11/2015
2	Polyuria 07/2014 - 10/2009
2	Neoplasms (Cancer) 09/2011 - 05/2008
2	Colonic Neoplasms (Colon Cancer) 09/2011 - 05/2008
2	Cocaine-Related Disorders (Cocaine Addiction) 03/2010 - 10/2003
2	Atrophy 11/2009 - 01/2009
2	Hypersensitivity (Allergy) 05/2005 - 12/2003
2	Lung Diseases (Lung Disease) 05/2005 - 12/2003
2	Bradycardia 04/2004 - 04/2003
2	Hypothermia 04/2003 - 04/2003
2	Tremor (Tremors) 04/2003 - 04/2003
1	Metabolic Diseases (Metabolic Disease) 01/2020
1	Edema (Dropsy) 10/2019
1	Cardiac Arrhythmias (Arrythmia) 10/2019
1	Hemolysis 01/2019
1	Anemia 01/2019
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2019
1	Peripheral Nervous System Diseases (PNS Diseases) 02/2017
1	Mitochondrial Diseases (Mitochondrial Disease) 02/2017
1	Infections 01/2015
1	Bacterial Infections (Bacterial Infection) 01/2015
1	Hyperoxia 06/2014
1	Bronchopulmonary Dysplasia 06/2014
1	Psychotic Disorders (Schizoaffective Disorder) 06/2014
1	Metaplasia 04/2014
1	Airway Remodeling 04/2014
1	Fragile X Syndrome (Martin Bell Syndrome) 03/2012

Drug/Important Bio-Agent (IBA)

26	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 10/2019 - 04/2003
20	Glucose (Dextrose)FDA LinkGeneric 10/2022 - 11/2006
19	Cholinergic Agents (Cholinergics)IBA 01/2019 - 04/2003
8	Insulin (Novolin)FDA Link 01/2022 - 06/2006
5	Pharmaceutical PreparationsIBA 12/2020 - 04/2011
4	GTP-Binding Proteins (G-Protein)IBA 01/2021 - 05/2010
4	ArrestinIBA 01/2021 - 05/2010
4	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2018 - 01/2009
4	Muscarinic M3 ReceptorIBA 01/2015 - 05/2008
3	Nonesterified Fatty Acids (NEFA)IBA 01/2022 - 01/2021
3	LigandsIBA 01/2021 - 04/2004
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 04/2010
3	Hypoglycemic Agents (Hypoglycemics)IBA 01/2020 - 01/2019
3	Cholinergic ReceptorsIBA 01/2019 - 12/2011
3	Antipsychotic Agents (Antipsychotics)IBA 09/2016 - 02/2010
3	Muscarinic M4 ReceptorIBA 01/2016 - 03/2012
3	Cholinergic Antagonists (Anticholinergics)IBA 01/2015 - 03/2006
3	Scopolamine (Hyoscine)FDA Link 09/2011 - 06/2010
3	Muscarinic AgonistsIBA 04/2004 - 04/2003
2	Blood Glucose (Blood Sugar)IBA 10/2021 - 06/2006
2	ArrestinsIBA 10/2019 - 01/2017
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2019 - 10/2012
2	Muscarinic AntagonistsIBA 02/2017 - 05/2010
2	Levodopa (L Dopa)FDA LinkGeneric 01/2016 - 11/2015
2	SmokeIBA 01/2015 - 12/2013
2	Vasopressins (Vasopressin)IBA 07/2014 - 10/2009
2	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 10/2009 - 05/2004
1	ClenbuterolIBA 10/2022
1	Adenosine A1 ReceptorIBA 10/2021
1	LipidsIBA 01/2021
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2020
1	Tolterodine Tartrate (Detrol)FDA Link 10/2019
1	Glucagon (Glukagon)FDA Link 01/2019
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2018
1	Adrenergic Agents (Adrenergic Drugs)IBA 08/2017
1	beta-Arrestin 1IBA 08/2017
1	muscarinic toxin 7IBA 02/2017
1	PirenzepineIBA 02/2017
1	HIV Envelope Protein gp120IBA 02/2017
1	Paclitaxel (Taxol)FDA LinkGeneric 02/2017
1	N- (3- oxo- 3- (4- (pyridin- 4- yl)piperazin- 1- yl)propyl)benzo(c)(1,2,5)thiadiazole- 4- sulfonamideIBA 02/2017
1	Neuropeptide YIBA 01/2016
1	Peptides (Polypeptides)IBA 01/2016
1	gamma-Aminobutyric Acid (GABA)IBA 01/2016
1	silmitasertibIBA 12/2015
1	Bronchodilator Agents (Bronchodilators)IBA 01/2015
1	Fluvastatin FDA Link 07/2014
1	Secretin FDA Link 07/2014
1	Oxidants (Oxidizing Agents)IBA 06/2014
1	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2014
1	AllergensIBA 04/2014
1	Fibronectins (Fibronectin)IBA 04/2014
1	CytokinesIBA 04/2014
1	CollagenIBA 04/2014
1	Streptozocin (Streptozotocin)FDA Link 08/2013
1	LeptinIBA 01/2013

Therapy/Procedure

4	Therapeutics 01/2021 - 01/2019
2	Drug Therapy (Chemotherapy) 10/2012 - 03/2010